By Carl D. Regillo MD
Studies the fundamental anatomy of the retina and diagnostic techniques to retinal ailment. comprises large examinations of problems of the retina and vitreous, together with ailment, irritation, hereditary dystrophies, abnormalities and trauma. Discusses laser remedy and vitreoretinal surgical procedure. final significant revision 2008-2009.
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Additional info for 2011-2012 Basic and Clinical Science Course, Section 12: Retina and Vitreous (Basic & Clinical Science Course)
Fish man GA, Birch DG, Holder GE, Brigell MG . Electrophysiologic Testing in Disorders of the Retina, Optic Nerve, and Visual Pathway. Ophthalmology Monograph 2. 2nd ed. San Fran cisco: American Academy of Ophthalmology; 200 l. Scholl HP, Zrenner E. Electrophysiology in the investigation of acquired retinal disorders. 2000;4N 9- 47 . Tzekov R. Ocular toxicity due to chloroquine and hydroxychloroquine: electrophysiological and visual function correlates. Doc Ophtha/mol. 2005;11 0:111-120. P" 50 msec Figure 3-5 Diag ram of th e pattern ERG (PERGI.
To obtain a fluorescein angiogram, white light from the camera flash unit is passed through a blue (excitatory) filter, and blue light enters the eye. The blue light, with its wavelength of 465- 490 11111, excites the unbound fluorescein molecules circulating in the retinal and choroidal layers or that have leaked out of the vasculature and stimulates them to emit a longer- wavele ngth yellow-green light (520-530 nm). Both the emitted yellow-green fluorescence and some degree of reflected blue light from structures that do not contain flu orescein exit the eye and return to the camera.
The transm ission of fl uorescence from drusen (see the small curved arrows in A) has faded. The large curved arrow shows staining of the scl era around the optic nerve. (Reproduced with permisSion from Bressler SB. age-related macular degenerarion IAMDJ and relatIVely good visual acuity. The Wilmer Retina Update. 1995; 1:3-7) 24 • Retina and Vitreous and is not visible. As fluorescein leaks into the space, the margins of the space trap the fluorescein and appear distinct, as seen, for example, in an RPE detachment in central serous chorioretinopathy (Fig 2-2D).