Basic and Clinical Science Course, 2008-2009, Section 4: by Debra J. Shetlar, Patricia Chevez-Barrios, Sander Dubovy,

By Debra J. Shetlar, Patricia Chevez-Barrios, Sander Dubovy, Robert H. Rosa, Jr, Nasreen Syed, Matthew W. Wilson, Ron W. Pelton, Jacob Pe'er

Discusses advances within the prognosis and class of tumors because it courses the reader via a logical, tissue-specific series that levels from topography via illness technique to common and differential prognosis. Many new colour pathologic and medical photos and diagrams spotlight this most modern revision. Covers wound fix; specimen dealing with, together with processing and marking; and diagnostic options. additionally encompasses a record for asking for ophthalmic pathologic session.

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Additional resources for Basic and Clinical Science Course, 2008-2009, Section 4: Ophthalmic Pathology and Intraocular Tumors

Sample text

Extracellular deposits may result from cellular overproduction of normal material or metabolically abnormal material. These processes, which have a variety of pathologic appearances, may occur in response to an injury or an inflammatory process. As used in this book, "degeneration" is an artificial category used to encompass a wide variety of disease processes. Various categories of diseases, such as those due to vascular causes, normal aging or involutional causes, and trauma, could be considered separately.

Tissue Processing The infiltration and embedding process removes most of the water from the tissue and replaces the water with paraffin. Organic solvents used in this process will dissolve lipid and may dissolve some synthetic materials. Routine processing usually dissolves intraocular lenses made of polymethylmethacrylate (PMMA), polypropylene, and silicone, although the PMMA may fall out during sectioning. Silk, nylon, and other synthetic sutures do not dissolve during routine processing. Specimens are routinely processed through increasing concentrations of alcohol followed by xylene or another clearing agent prior to infiltration with paraffin.

19 limited list of specific conditions resulting from pathologic processes that were identified in the general diagnosis. For instance, the differential diagnosis based on the features of noncaseating granulomatous inflammation of the conjunctiva includes sarcoidosis, foreign body, fungus, and mycobacterium. The differential diagnosis of melanocytic proliferation of the conjunctiva includes nevus, primary acquired melanosis, and melanoma. Readers are encouraged to practice working through the hierarchical framework by verbalizing each step in sequence while examining a pathologic specimen.

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